May 27, 2020 | 11AM-12PM | Spring 2020 NANOFANS Webinar Series - “Nanotechnology in Infectious Diseases (Diagnostics/Therapeutics)”: Session 5 - “Virus-Like Particle Approaches to Coronavirus Diagnostics and Vaccines”
M.G. Finn, Professor of Chemistry & Biochemistry; Georgia Institute of Technology
"Spring 2020 NanoFANS (Focusing on Advanced Nanobio- Systems) program will be offered in a weekly webinar format during the month of May. The focus of this event will be “Nanotechnology in Infectious Diseases (Diagnostics/Therapeutics).”
In the current global pandemic situation, infectious diseases are the leading cause of mortality worldwide, with viruses such as, ebola, SARS-Cov, SARS-Cov-2 in particular, making global impact on healthcare and socio-economic development. The rapid development of drug resistance to currently available therapies and associated side effects leads to serious public health concern; hence, devising novel treatment strategies is of paramount importance. The application of nanotechnology in infectious diseases is fast-revolutionizing the biomedical field and the healthcare sector and has a potential to diagnose, treat and prevent diseases."
Abstract: Virus detection and immunization both require exquisite molecular recognition of virus-specific structures. Achieving such recognition is one of the chief functions of the immune system. Over the past three months, we have asked the mouse immune system to accomplish this, in a straightforward but intense series of experiments focused on the obvious coronavirus target: the “spike” protein that the pathogen uses to interact with and invade human cells. The general approach, platform design and manufacture, and current results will be described, along with a discussion of where we and others may go next in the rapid development of SARS-nCoV-2 detection and therapy.
Bio: M.G. Finn received his Ph.D. degree in 1986 from the Massachusetts Institute of Technology working with Prof. K.B. Sharpless, followed by an NIH postdoctoral fellowship with Prof. J.P. Collman at Stanford University. He joined the faculty of the University of Virginia in 1988, where his group studied and developed a variety of transition metal-
mediated processes. Prof. Finn moved to the Department of Chemistry and The Skaggs Institute for Chemical Biology at The Scripps Research Institute in 1998, and then to the School of Chemistry & Biochemistry and the School of Biology at Georgia Tech in 2013. His current interests include the use of virus particles as molecular and catalytic building blocks for vaccine and functional materials development, the discovery of click reactions for organic and materials synthesis, polyvalent interactions in drug targeting, and the use of evolution for the discovery of chemical function. He was the first recipient of the annual Scripps Outstanding Mentor Award, and is Editor-in- Chief of the journal ACS Combinatorial Science.
Registration Link: https://tinyurl.com/nanofanswebinar
Event Address: Webinar link will be sent to all those registered prior to the event